Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 8/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | CASP2 | P42575 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25453158 | 0.83 | PAOX (0.52) | PAOXADRA1AMAPK1KDM4EHIF1A | |
| SCHEMBL13311546 | 0.83 | PAOX (0.52) | PAOXADRA1AMAPK1KDM4EHIF1A | |
| SCHEMBL23729381 | 0.83 | PAOX (0.52) | PAOXADRA1AMAPK1KDM4EHIF1A | |
| SCHEMBL25090250 | 0.83 | PAOX (0.52) | PAOXADRA1AMAPK1KDM4EHIF1A | |
| SCHEMBL25453657 | 0.83 | PAOX (0.52) | PAOXADRA1AMAPK1KDM4EHIF1A | |
| SCHEMBL25453230 | 0.83 | PAOX (0.52) | PAOXADRA1AMAPK1KDM4EHIF1A | |
| SCHEMBL13662526 | 0.81 | PAOX (0.48) | PAOXADRA1AMAPK1KDM4EHIF1A | |
| SCHEMBL21791082 | 0.75 | LMNA (0.42) | ADRA1AALDH1A1MEN1KMT2APRMT1 | |
| SCHEMBL13287153 | 0.75 | PAOX (0.52) | PAOXADRA1AMAPK1KDM4EHIF1A | |
| SCHEMBL15773958 | 0.74 | PAOX (0.47) | PAOXADRA1AMAPK1MEN1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392428-B2 | GLP-1 derivatives and uses thereof | NOVO NORDISK A/S (DK) | 2019-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392428-B2 | GLP-1 derivatives and uses thereof | GLP1R, GIPR, VIP | PAOX 1068/4885ADRA1A 1357/4885MAPK1 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.