Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.40 |
| ▸ | DRD4 | P21917 | 8/20 | 0.37 |
| ▸ | DRD3 | P35462 | 8/20 | 0.37 |
| ▸ | DRD1 | P21728 | 6/20 | 0.37 |
| ▸ | DRD5 | P21918 | 6/20 | 0.37 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21297621 | 1.00 | DRD2 (0.40) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL13481209 | 0.84 | DRD2 (0.38) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL21326449 | 0.81 | DRD2 (0.33) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL25418364 | 0.81 | DRD2 (0.33) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL22529697 | 0.81 | DRD2 (0.33) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL16041190 | 0.76 | NR1H2 (0.36) | — | |
| SCHEMBL431871 | 0.76 | NR1H2 (0.36) | — | |
| SCHEMBL16050778 | 0.76 | NR1H2 (0.36) | — | |
| SCHEMBL4758581 | 0.73 | GAA (0.42) | — | |
| SCHEMBL16687101 | 0.73 | DRD2 (0.32) | DRD2DRD4DRD3DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019163865-A1 | DIBENZAZEPINE DERIVATIVE HAVING NITROGEN-CONTAINING HETEROCYCLIC RING | 大日本住友製薬株式会社 | 2019-08-29 | — | — | WO | disclosed |