Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21163130 | 0.83 | — | — | |
| SCHEMBL20683211 | 0.75 | MEN1 (0.32) | MAPT | |
| SCHEMBL22606192 | 0.73 | MAPT (0.35) | MAPT | |
| SCHEMBL21972869 | 0.73 | POLB (0.34) | POLB | |
| SCHEMBL10160139 | 0.72 | POLB (0.32) | POLB | |
| SCHEMBL18134951 | 0.69 | POLB (0.32) | POLB | |
| SCHEMBL21887534 | 0.66 | MAPT (0.30) | MAPT | |
| SCHEMBL10211148 | 0.65 | POLB (0.35) | POLBMAPT | |
| SCHEMBL1106105 | 0.64 | MAPT (0.31) | POLBMAPT | |
| SCHEMBL10103000 | 0.64 | MAPT (0.31) | POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392421-B2 | Cytotoxic peptides and conjugates thereof | NOVARTIS AG (CH) | 2019-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392421-B2 | Cytotoxic peptides and conjugates thereof | CD47, NGLY1, VIP | POLB 3250/4885MAPT 3197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.