Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14450839 | 0.70 | ACE (0.32) | — | |
| SCHEMBL20683211 | 0.70 | MEN1 (0.32) | MAPT | |
| SCHEMBL22606192 | 0.68 | MAPT (0.35) | MAPT | |
| SCHEMBL18850497 | 0.67 | ACE (0.32) | — | |
| SCHEMBL21298846 | 0.66 | POLB (0.33) | MAPT | |
| SCHEMBL16132739 | 0.66 | GAA (0.33) | MAPT | |
| SCHEMBL258692 | 0.64 | MGLL (0.36) | — | |
| SCHEMBL14437893 | 0.63 | POLB (0.32) | MAPT | |
| SCHEMBL20822260 | 0.62 | ADAM17 (0.41) | MAPT | |
| SCHEMBL18721647 | 0.62 | POLB (0.34) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11370801-B2 | Pyrrolobenzodiazepine conjugates | MEDIMMUNE LIMITED (GB) | 2022-06-28 | — | — | US | disclosed |
| US-20200115390-A1 | PYRROLOBENZODIAZEPINE CONJUGATES | MEDIMMUNE LIMITED (GB) | 2020-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11370801-B2 | Pyrrolobenzodiazepine conjugates | NR0B2, HRH3, NR0B1 | MAPT 3731/4885 |
| US-20200115390-A1 | PYRROLOBENZODIAZEPINE CONJUGATES | NR0B2, HRH3, NR0B1 | MAPT 3731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.