Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.45 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.45 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.45 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.45 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25967106 | 0.92 | POLB (0.53) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL22352121 | 0.92 | POLB (0.54) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL20763160 | 0.92 | POLB (0.54) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL20691275 | 0.91 | BCHE (0.52) | POLBENPP1P2RY1BCHEDNPH1 | |
| SCHEMBL21299326 | 0.89 | POLB (0.49) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL23477857 | 0.88 | POLB (0.50) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL24325561 | 0.88 | POLB (0.53) | POLBENPP1P2RY1 | |
| SCHEMBL22349189 | 0.88 | POLB (0.51) | POLBENPP1P2RY1DNPH1PRKAB2 | |
| SCHEMBL24322613 | 0.88 | POLB (0.40) | POLBENPP1P2RY1BCHE | |
| SCHEMBL24322645 | 0.87 | POLB (0.44) | POLBENPP1P2RY1BCHEDNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169693-B1 | CHIMERIC POLYNUCLEOTIDES | MODERNATX INC (US) | 2022-03-09 | — | — | EP | disclosed |
| EP-3169335-B1 | CIRCULAR POLYNUCLEOTIDES | MODERNA THERAPEUTICS INC (US) | 2019-08-28 | — | — | EP | disclosed |