SCHEMBL24325561

SCHEMBL24325561

COP(=O)(O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C[C@@H]1OP(=O)(O)OC[C@@H]1CC[C@H](n2cnc3c(N)ncnc32)O1

nearest known ligand 0.61

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.53
▸ P2RY1 P47900 3/20 0.51
▸ RNASEL Q05823 2/20 0.51
▸ ENPP1 P22413 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25582525 0.94 RNASEL (0.57) POLBP2RY1RNASEL
SCHEMBL25786818 0.92 POLB (0.59) POLBP2RY1ENPP1
SCHEMBL18822882 0.92 TERT (0.52) POLB
SCHEMBL17122136 0.90 POLB (0.56) POLBP2RY1RNASELENPP1
SCHEMBL22352146 0.90 P2RY1 (0.54) POLBP2RY1
SCHEMBL20692157 0.90 P2RY1 (0.54) POLBP2RY1
SCHEMBL21447399 0.89 POLB (0.56) POLBP2RY1RNASELENPP1
SCHEMBL17122140 0.88 POLB (0.58) POLBP2RY1ENPP1
SCHEMBL21299334 0.88 POLB (0.50) POLBP2RY1ENPP1
SCHEMBL21540035 0.88 ALDH1A1 (0.51) POLBP2RY1RNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3169693-B1 CHIMERIC POLYNUCLEOTIDES MODERNATX INC (US) 2022-03-09 — — EP disclosed
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