SCHEMBL213002

SCHEMBL213002

CC/C(C)=N/O[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.38
LMNA P02545 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ATM Q13315 1/20 0.34
MAOA P21397 2/20 0.33
MAPT P10636 3/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL213003 1.00 MAOB (0.38) MAOBLMNAMAPK1HTTL3MBTL1
SCHEMBL2050543 0.87 LMNA (0.36) MAOBLMNAMAPK1HTTL3MBTL1
SCHEMBL2050414 0.87 MAPT (0.39) LMNAMAPK1HTTL3MBTL1MAPT
SCHEMBL2050541 0.87 LMNA (0.36) MAOBLMNAMAPK1HTTL3MBTL1
SCHEMBL2050412 0.87 MAPT (0.39) LMNAMAPK1HTTL3MBTL1MAPT
SCHEMBL29488783 0.85 MAOB (0.38) MAOBLMNAMAPK1HTTL3MBTL1
SCHEMBL531137 0.85 MAOB (0.38) MAOBLMNAMAPK1HTTL3MBTL1
SCHEMBL3300226 0.85 MAOB (0.38) MAOBLMNAMAPK1HTTL3MBTL1
SCHEMBL2044132 0.85 MAOB (0.33) MAOBLMNAMAPK1HTTL3MBTL1
SCHEMBL2044130 0.85 MAOB (0.33) MAOBLMNAMAPK1HTTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US claimed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US claimed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US disclosed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US disclosed