Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | MIF | P14174 | 4/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15066827 | 1.00 | BCL2A1 (0.40) | BCL2A1ESR2MIFBRD4CREBBP | |
| SCHEMBL15066310 | 0.87 | NPC1 (0.46) | ESR2MIFSTSALDH1A1KDM4E | |
| SCHEMBL15066787 | 0.86 | MIF (0.54) | BCL2A1MIFALDH1A1KDM4EHPGD | |
| SCHEMBL15066949 | 0.86 | ESR2 (0.44) | ESR2MIFSTSALDH1A1KDM4E | |
| SCHEMBL15086320 | 0.85 | NPC1 (0.46) | ESR2MIFSTSALDH1A1KDM4E | |
| SCHEMBL15066699 | 0.83 | HSD11B1 (0.43) | BCL2A1MIFALDH1A1KDM4EMEN1 | |
| SCHEMBL15066761 | 0.82 | NPC1 (0.56) | MIFALDH1A1KDM4EMEN1HPGD | |
| SCHEMBL15069112 | 0.82 | MAPT (0.48) | ESR2MIFALDH1A1KDM4EMEN1 | |
| SCHEMBL15068939 | 0.82 | MAPT (0.56) | ESR2MIFBRD4CREBBPALDH1A1 | |
| SCHEMBL15065845 | 0.82 | MAPT (0.48) | ESR2MIFALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797592-B1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS INC (US) | 2019-08-28 | — | — | EP | disclosed |