Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15066685 | 0.91 | MAOB (0.48) | ACHEALKMIFNPC1RAB9A | |
| SCHEMBL15068980 | 0.77 | ADRB1 (0.49) | ALKMIFNPC1RAB9AMEN1 | |
| SCHEMBL30708181 | 0.75 | NPC1 (0.61) | ACHEALKMIFNPC1RAB9A | |
| SCHEMBL15067192 | 0.75 | NPC1 (0.61) | ACHEALKMIFNPC1RAB9A | |
| SCHEMBL30708179 | 0.75 | NPC1 (0.61) | ACHEALKMIFNPC1RAB9A | |
| SCHEMBL15066757 | 0.75 | ALK (0.44) | ALKNPC1RAB9AMEN1KMT2A | |
| SCHEMBL15069364 | 0.74 | NPC1 (0.53) | ALKNPC1RAB9A | |
| SCHEMBL15066958 | 0.73 | ALK (0.46) | ACHEALKMIFNPC1RAB9A | |
| SCHEMBL27262075 | 0.73 | MIF (0.57) | ACHEMIFNPC1RAB9AMEN1 | |
| SCHEMBL27262381 | 0.72 | MIF (0.56) | MIFNPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797592-B1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS INC (US) | 2019-08-28 | — | — | EP | disclosed |