Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 5/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.35 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15066801 | 0.93 | ADORA2A (0.38) | DRD2DRD3ALKDRD4SLC16A3 | |
| SCHEMBL15065855 | 0.92 | RXFP1 (0.40) | DRD2DRD3ALKDRD4SLC16A3 | |
| SCHEMBL15069127 | 0.90 | ALK (0.38) | DRD2DRD3ALKSLC16A3 | |
| SCHEMBL15068774 | 0.90 | ADORA2A (0.38) | DRD2DRD3ALKDRD4SLC16A3 | |
| SCHEMBL15068777 | 0.86 | ADORA2A (0.39) | DRD2DRD3ALKSLC16A3 | |
| SCHEMBL15068560 | 0.86 | ACVR1 (0.40) | ALKSLC16A3 | |
| SCHEMBL15069031 | 0.85 | ALK (0.37) | ALKSLC16A3 | |
| SCHEMBL15068834 | 0.83 | CHRNB2 (0.39) | ALKSLC16A3 | |
| SCHEMBL15068519 | 0.82 | ALK (0.35) | ALKSLC16A3 | |
| SCHEMBL15068713 | 0.82 | ACVR1 (0.36) | ALKSLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797592-B1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS INC (US) | 2019-08-28 | — | — | EP | disclosed |