Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 10/20 | 0.40 |
| ▸ | CDK1 | P06493 | 9/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15828265 | 0.80 | CDK2 (0.41) | CDK2CDK1CCNB1CCNE1ADORA2A | |
| SCHEMBL28192314 | 0.79 | CDK2 (0.40) | CDK2CDK1CCNB1CCNE1ADORA2A | |
| SCHEMBL6364047 | 0.79 | CDK2 (0.56) | CDK2CDK1CCNB1CCNE1ADORA2A | |
| SCHEMBL27984740 | 0.79 | CDK1 (0.43) | CDK2CDK1CCNB1CCNE1ADORA2A | |
| SCHEMBL1496411 | 0.79 | CDK2 (0.46) | CDK2CDK1CCNB1CCNE1ADORA2A | |
| SCHEMBL17807736 | 0.79 | CDK2 (0.40) | CDK2CDK1CCNB1CCNE1ADORA2A | |
| SCHEMBL21311457 | 0.77 | ADA (0.39) | KDM4E | |
| SCHEMBL12831960 | 0.76 | CYP1A2 (0.50) | CDK2CDK1CCNB1CCNE1MAPK1 | |
| SCHEMBL18510356 | 0.76 | CDK1 (0.38) | CDK2CDK1CCNB1CCNE1ADORA2A | |
| SCHEMBL18510348 | 0.76 | CYP1A2 (0.50) | CDK2CDK1CCNB1CCNE1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190262371-A1 | METHODS AND COMPOSITION FOR THE TREATMENT OF RNA VIRAL INFECTIONS | POLRMT, EIF2AK2, NSUN3 | CDK2 4322/4885CDK1 4187/4885CCNB1 4396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.