Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3177993 | 0.81 | TDP1 (0.46) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL16923544 | 0.77 | TDP1 (0.55) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL22939663 | 0.77 | TDP1 (0.46) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL8983076 | 0.76 | TDP1 (0.44) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL14978979 | 0.76 | MEN1 (0.46) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL16923542 | 0.76 | TDP1 (0.44) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL10073751 | 0.76 | TDP1 (0.53) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL16013856 | 0.74 | TDP1 (0.43) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL17574265 | 0.74 | TDP1 (0.50) | TDP1MEN1KMT2AGAAMAOA | |
| SCHEMBL10117371 | 0.74 | TDP1 (0.50) | TDP1MEN1KMT2AGAAMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019165290-A1 | PYRIDINE-SULFONAMIDE COMPOUNDS AND THEIR USE AGAINST PAIN AND RELATED CONDITIONS | GENENTECH, INC. (US) | 2019-08-29 | — | — | WO | disclosed |