Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | BTK | Q06187 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RBP4 | P02753 | 9/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20106543 | 0.86 | KMT2A (0.53) | KMT2AL3MBTL1BTKKDM1AMAOB | |
| SCHEMBL21232389 | 0.86 | KMT2A (0.53) | KMT2AL3MBTL1BTKKDM1AMAOB | |
| SCHEMBL20106544 | 0.84 | KMT2A (0.53) | KMT2AL3MBTL1BTKKDM1AMAOB | |
| SCHEMBL21232390 | 0.83 | KMT2A (0.52) | KMT2AL3MBTL1BTKKDM1AMAOB | |
| SCHEMBL21306745 | 0.83 | LMNA (0.44) | KMT2AL3MBTL1KDM1AMAOBLMNA | |
| SCHEMBL20106566 | 0.83 | KMT2A (0.52) | KMT2AL3MBTL1BTKKDM1AMAOB | |
| SCHEMBL21307080 | 0.83 | LMNA (0.44) | KMT2AL3MBTL1KDM1AMAOBLMNA | |
| SCHEMBL21232478 | 0.81 | BTK (0.60) | KMT2AL3MBTL1BTKKDM1AMAOB | |
| SCHEMBL21232399 | 0.81 | BTK (0.60) | KMT2AL3MBTL1BTKKDM1AMAOB | |
| SCHEMBL21232569 | 0.79 | BTK (0.52) | KMT2AL3MBTL1BTKKDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019165290-A1 | PYRIDINE-SULFONAMIDE COMPOUNDS AND THEIR USE AGAINST PAIN AND RELATED CONDITIONS | GENENTECH, INC. (US) | 2019-08-29 | — | — | WO | disclosed |