Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | CETP | P11597 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2132932 | 1.00 | ENPP2 (0.51) | ENPP2PLK1THRBTHRACETP | |
| SCHEMBL8151307 | 1.00 | ENPP2 (0.51) | ENPP2PLK1THRBTHRACETP | |
| SCHEMBL1548161 | 1.00 | ENPP2 (0.51) | ENPP2PLK1THRBTHRACETP | |
| SCHEMBL3919113 | 1.00 | ENPP2 (0.51) | ENPP2PLK1THRBTHRACETP | |
| SCHEMBL272121 | 0.94 | TRPV1 (0.48) | — | |
| SCHEMBL1958089 | 0.94 | TRPV1 (0.48) | — | |
| SCHEMBL8083264 | 0.94 | ENPP2 (0.57) | ENPP2THRBTHRAHTR2AS1PR1 | |
| SCHEMBL11067476 | 0.94 | ENPP2 (0.57) | ENPP2THRBTHRAHTR2AS1PR1 | |
| SCHEMBL11063910 | 0.94 | ENPP2 (0.57) | ENPP2THRBTHRAHTR2AS1PR1 | |
| SCHEMBL11068357 | 0.94 | ENPP2 (0.57) | ENPP2THRBTHRAHTR2AS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2446005-B1 | ANTI-WEAR AGENTS WITH A REDUCED NEUROTOXICITY | NYCO (FR) | 2015-04-29 | — | — | EP | disclosed |
| EP-2446005-A1 | ANTI-WEAR AGENTS WITH A REDUCED NEUROTOXICITY | Nyco SA (FR) | 2012-05-02 | — | — | EP | disclosed |
| US-20120101015-A1 | ANTI-WEAR AGENTS WITH A REDUCED NEUROTOXICITY | NYCO SA (FR) | 2012-04-26 | — | — | US | disclosed |
| WO-2010149690-A1 | ANTI-WEAR AGENTS WITH A REDUCED NEUROTOXICITY | NYCO SA (FR) | 2010-12-29 | — | — | WO | disclosed |
| US-6093760-A | LOW VOLATILITY FLAME RETARDANT FOR A STYRENE RESIN COMPRISING HYDROGEN OR HALOGEN OR HALOGEN-FREE 1-30 CARBON ATOMS SUBSTITUTED TRIPHENYLPHOSPHATE, WHERE THE SUBSTITUENTS IN EACH PHENYL ARE DIFFERENT | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2000-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101015-A1 | ANTI-WEAR AGENTS WITH A REDUCED NEUROTOXICITY | SSB, PRNP, TARDBP | ENPP2 143/4885PLK1 3288/4885THRB 2059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.