Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 8/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 8/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3577125 | 0.94 | ALDH1A1 (0.66) | RXFP1KDM4EALDH1A1POLBNPSR1 | |
| SCHEMBL2302252 | 0.86 | RXFP1 (1.00) | RXFP1KDM4EALDH1A1POLBNPSR1 | |
| SCHEMBL2302494 | 0.81 | RXFP1 (0.73) | RXFP1KDM4EALDH1A1POLBNPSR1 | |
| SCHEMBL2301933 | 0.79 | ALDH1A1 (0.67) | RXFP1KDM4EALDH1A1POLBNPSR1 | |
| SCHEMBL2302031 | 0.76 | ALDH1A1 (0.78) | RXFP1KDM4EALDH1A1POLBNPSR1 | |
| SCHEMBL189608 | 0.76 | ALDH1A1 (1.00) | RXFP1KDM4EALDH1A1POLBNPSR1 | |
| SCHEMBL189044 | 0.75 | RXFP1 (1.00) | RXFP1KDM4EALDH1A1POLBNPSR1 | |
| SCHEMBL2304540 | 0.75 | PIK3CG (0.72) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL10044528 | 0.75 | RXFP1 (1.00) | RXFP1KDM4EALDH1A1POLBNPSR1 | |
| SCHEMBL3625455 | 0.74 | RXFP1 (0.72) | RXFP1KDM4EALDH1A1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118076-B1 | QUINOXALINE COMPOUNDS AND USE THEREOF | MERCK SERONO SA (CH) | 2019-09-04 | — | — | EP | claimed |