SCHEMBL21313705

SCHEMBL21313705

O=C(c1ccccc1)c1ccc(C(=O)N2C(c3ccccc3Cl)CC[C@H]2C(=O)O)cc1

nearest known ligand 0.82

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 20/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29787744 1.00 FFAR2 (0.82) FFAR2
SCHEMBL2039679 1.00 FFAR2 (0.82) FFAR2
SCHEMBL2039678 1.00 FFAR2 (0.82) FFAR2
SCHEMBL2049825 0.90 FFAR2 (1.00) FFAR2
SCHEMBL29788058 0.90 FFAR2 (1.00) FFAR2
SCHEMBL29787831 0.90 FFAR2 (1.00) FFAR2
SCHEMBL14635536 0.90 FFAR2 (1.00) FFAR2
SCHEMBL2050445 0.88 FFAR2 (0.91) FFAR2
SCHEMBL29787534 0.88 FFAR2 (0.91) FFAR2
SCHEMBL13369763 0.87 FFAR2 (0.85) FFAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3074008-B1 COMPOUNDS, PHARMACEUTICAL COMPOSITION AND METHODS FOR USE IN TREATING INFLAMMATION EPICS THERAPEUTICS (BE) 2019-09-04 EP claimed