SCHEMBL21314979

SCHEMBL21314979

O=C(O)c1cn(Cc2cccc(C(F)(F)F)c2)cn1

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 3/20 0.67
CYP3A4 P08684 1/20 0.48
CYP2C9 P11712 1/20 0.48
P2RY14 Q15391 1/20 0.47
NR4A2 P43354 2/20 0.47
KMO O15229 1/20 0.45
SCD O00767 1/20 0.45
ATM Q13315 1/20 0.44
PTGER1 P34995 1/20 0.44
KDM4A O75164 1/20 0.44
FAAH O00519 1/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
HDAC3 O15379 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30504022 1.00 KDM4C (0.67) KDM4CCYP3A4CYP2C9P2RY14NR4A2
SCHEMBL24208400 0.84 KDM4C (0.47) KDM4CP2RY14KDM4AKDM4E
SCHEMBL15957010 0.83 KDM4C (0.65) KDM4CP2RY14NR4A2SCDKDM4A
SCHEMBL23188813 0.83 KDM4C (0.46) KDM4CCYP3A4CYP2C9SCDKDM4A
Trifluoroacetic Acid SCHEMBL4737904 0.81 KDM4C (0.50) KDM4CCYP3A4CYP2C9SCDKDM4A
SCHEMBL3688462 0.80 KDM4C (0.57) KDM4CCYP3A4CYP2C9KDM4AGAA
SCHEMBL16032991 0.80 KDM4C (1.00) KDM4CNR4A2KDM4A
SCHEMBL21314995 0.80 KDM4C (0.50) KDM4CP2RY14KDM4AKDM4EALDH1A1
SCHEMBL30504034 0.80 KDM4C (0.50) KDM4CP2RY14KDM4AKDM4EALDH1A1
SCHEMBL15707369 0.79 KDM4C (0.56) KDM4CCYP3A4CYP2C9KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113994970-B Substituted sulfonamides for combating animal pests 拜耳公司 2023-05-12 CN disclosed
CN-113994970-A Substituted sulfonamides for combating animal pests 拜耳公司 2022-02-01 CN disclosed
EP-3534709-B1 SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS BAYER AG (DE) 2021-06-16 EP disclosed
US-10820591-B2 Substituted sulfonyl amides for controlling animal pests BAYER AKTIENGESELLSCHAFT (DE) 2020-11-03 US disclosed
EP-3534709-A1 SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS Bayer Aktiengesellschaft (DE) 2019-09-11 EP disclosed
US-20190269134-A1 SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS BAYER AKTIENGESELLSCHAFT (DE) 2019-09-05 US disclosed
CN-110191639-A Substituted sulfonamides for combating animal pests 拜耳公司 2019-08-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190269134-A1 SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS MLYCD, STOM, DDT KDM4C 703/4885CYP3A4 2644/4885CYP2C9 1551/4885
US-10820591-B2 Substituted sulfonyl amides for controlling animal pests MLYCD, STOM, DDT KDM4C 703/4885CYP3A4 2644/4885CYP2C9 1551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.