Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1866054 | 0.89 | PARP1 (0.72) | PARP1PARP2 | |
| SCHEMBL21318540 | 0.84 | PARP1 (0.79) | PARP1PARP2 | |
| SCHEMBL21318541 | 0.84 | PARP1 (0.58) | PARP1PARP2 | |
| SCHEMBL21318523 | 0.80 | PARP1 (0.79) | PARP1PARP2 | |
| SCHEMBL21318558 | 0.79 | PARP2 (0.58) | PARP1PARP2 | |
| SCHEMBL21318684 | 0.79 | PARP1 (0.77) | PARP1PARP2 | |
| SCHEMBL21318525 | 0.79 | PARP1 (0.57) | PARP1PARP2 | |
| SCHEMBL21318556 | 0.78 | PARP1 (0.79) | PARP1PARP2 | |
| SCHEMBL21318450 | 0.78 | PARP1 (0.59) | PARP1PARP2 | |
| SCHEMBL21318543 | 0.78 | POLB (0.66) | PARP1PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2454236-B1 | 3-OXO-2,3-DIHYDRO-1H-ISOINDOLE-4-CARBOXAMIDES AS PARP INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2019-09-04 | — | — | EP | disclosed |