SCHEMBL21318923

SCHEMBL21318923

CC(=O)NC1C(O)CC(OC2C(O)C(CO)OC(OC(C(O)CO)C(O)C(O)C=O)C2O)(C(=O)O)OC1C(O)C(O)CO

nearest known ligand 0.62

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MAG P20916 12/20 0.62
▸ SIGLEC7 Q9Y286 6/20 0.58
▸ SELL P14151 1/20 0.55
▸ SELP P16109 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21318889 1.00 MAG (0.62) MAGSIGLEC7SELLSELP
SCHEMBL8673965 1.00 MAG (0.62) MAGSIGLEC7SELLSELP
SCHEMBL29358356 0.96 MAG (0.64) MAGSIGLEC7SELLSELP
SCHEMBL29790139 0.95 SIGLEC7 (0.63) MAGSIGLEC7SELLSELP
SCHEMBL29809799 0.95 SIGLEC7 (0.63) MAGSIGLEC7SELLSELP
SCHEMBL29540690 0.94 MAG (0.64) MAGSIGLEC7SELLSELP
SCHEMBL30206509 0.93 MAG (0.70) MAGSIGLEC7
SCHEMBL29395515 0.93 MAG (0.61) MAGSIGLEC7SELLSELP
SCHEMBL27420908 0.93 MAG (0.64) MAGSIGLEC7SELLSELP
SCHEMBL23857822 0.88 MAG (0.62) MAGSIGLEC7SELLSELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220143056-A1 METHODS AND THERAPIES FOR TREATING ATHEROSCLEROSIS AND/OR HYPERLIPIDEMIA USING OLIGOSACCHARIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-05-12 — — US disclosed
US-11234992-B2 Methods and therapies for treating atherosclerosis and/or hyperlipidemia using oligosaccharides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-02-01 — — US disclosed
US-20190269713-A1 METHODS AND THERAPIES FOR TREATING ATHEROSCLEROSIS AND/OR HYPERLIPIDEMIA USING OLIGOSACCHARIDES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-09-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190269713-A1 METHODS AND THERAPIES FOR TREATING ATHEROSCLEROSIS AND/OR HYPERLIPIDEMIA USING OLIGOSACCHARIDES APOB, LDLR, PCSK9 MAG 655/4885SIGLEC7 83/4885SELL 76/4885
US-11234992-B2 Methods and therapies for treating atherosclerosis and/or hyperlipidemia using oligosaccharides APOB, LDLR, PCSK9 MAG 655/4885SIGLEC7 83/4885SELL 76/4885
US-20220143056-A1 METHODS AND THERAPIES FOR TREATING ATHEROSCLEROSIS AND/OR HYPERLIPIDEMIA USING OLIGOSACCHARIDES APOB, LDLR, PCSK9 MAG 655/4885SIGLEC7 83/4885SELL 76/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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