Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 4/20 | 0.39 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17714945 | 0.92 | KDM4E (0.46) | KDM4ETDP1AURKAAHRGRM5 | |
| SCHEMBL17918417 | 0.85 | AHR (0.47) | KDM4EAHRKIF11TSHRHSD17B10 | |
| SCHEMBL17918418 | 0.83 | MAPT (0.43) | AHRKIF11MAPTKMT2AALDH1A1 | |
| SCHEMBL15786374 | 0.82 | MEN1 (0.46) | KDM4EAURKAAHRKIF11MAPT | |
| SCHEMBL30411263 | 0.82 | AHR (0.50) | KDM4EAURKAAHRKIF11ADORA3 | |
| SCHEMBL4871050 | 0.82 | AHR (0.50) | KDM4EAURKAAHRKIF11ADORA3 | |
| SCHEMBL13154428 | 0.82 | KDM4E (0.69) | KDM4ETDP1GRM5METAP1MAPT | |
| SCHEMBL17918481 | 0.81 | HTR2B (0.43) | AHRTNK2KIF11MAPTKMT2A | |
| SCHEMBL17714956 | 0.80 | AHR (0.52) | KDM4EAHRKIF11MAPTSMN1; SMN2 | |
| SCHEMBL26451917 | 0.79 | AHR (0.41) | AHRKIF11HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3015465-B1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEMICAL LTD (KR) | 2019-09-04 | — | — | EP | disclosed |