SCHEMBL4871050

SCHEMBL4871050

c1ccc(-c2ccc3c(c2)[nH]c2ccccc23)nc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.50
AURKA O14965 2/20 0.48
KIF11 P52732 7/20 0.47
ALDH1A1 P00352 2/20 0.47
GPR3 P46089 1/20 0.47
HSD17B10 Q99714 1/20 0.47
LRRK2 Q5S007 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
MAPT P10636 2/20 0.45
PRMT5 O14744 2/20 0.44
WDR77 Q9BQA1 1/20 0.44
KDM4E B2RXH2 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
ACHE P22303 1/20 0.43
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43
IKBKB O14920 1/20 0.43
CHUK O15111 1/20 0.43
PIM1 P11309 1/20 0.43
TOP1 P11387 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30411263 1.00 AHR (0.50) AHRAURKAKIF11ALDH1A1GPR3
SCHEMBL12249863 0.90 AHR (0.50) AHRAURKAKIF11ALDH1A1GPR3
SCHEMBL19185823 0.84 CHEK1 (0.49) AURKAALDH1A1LRRK2ADORA3MAPT
Carbazole SCHEMBL28158156 0.84 ALDH1A1 (0.52) AHRAURKAALDH1A1GPR3HSD17B10
SCHEMBL28008725 0.84 AURKA (0.49) AHRAURKAKIF11ALDH1A1GPR3
Carbazole SCHEMBL12099644 0.84 KDM4E (0.61) AHRAURKAALDH1A1GPR3HSD17B10
Carbazole SCHEMBL28334621 0.84 KDM4E (0.61) AHRAURKAALDH1A1GPR3HSD17B10
Carbazole SCHEMBL29290202 0.83 ALDH1A1 (0.50) AHRAURKAALDH1A1GPR3HSD17B10
SCHEMBL28163146 0.83 GABRP (0.51) AHRAURKAKIF11ALDH1A1GPR3
SCHEMBL21320107 0.82 KDM4E (0.46) AHRAURKAKIF11ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4701391-A2 HETEROLEPTIC IRIDIUM COMPLEX Universal Display Corporation (US) 2026-02-25 EP disclosed
US-12550604-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-02-10 US disclosed
US-20260035398-A1 TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES UNIV ARIZONA STATE (US) 2026-02-05 US disclosed
EP-3643721-B1 HETEROLEPTIC IRIDIUM COMPLEX UNIVERSAL DISPLAY CORP (US) 2026-01-28 EP disclosed
US-12312366-B2 Tetradentate and octahedral metal complexes containing naphthyridinocarbazole and its analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2025-05-27 US disclosed
US-20240376140-A1 Metal Complexes, Methods, and Uses Thereof ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2024-11-14 US disclosed
US-12043633-B2 Metal complexes, methods, and uses thereof ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2024-07-23 US disclosed
US-11910701-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-20 US disclosed
EP-4306521-A1 CENTRAL CHIRALITY INDUCED SPIRO CHIRAL TETRADENTATE CYCLOMETALATED PLATINUM (II) AND PALLADIUM (II) COMPLEX-BASED CIRCULARLY POLARIZED LUMINESCENCE MATERIAL AND APPLICATION THEREOF Zhejiang University of Technology (CN) 2024-01-17 EP disclosed
US-20230309376-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-28 US disclosed
WO-2014109814-A9 METAL COMPLEXES, METHODS, AND USES THEREOF ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2014-08-14 WO disclosed
WO-2014109814-A9 METAL COMPLEXES, METHODS, AND USES THEREOF ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2014-08-14 WO disclosed
WO-2014109814-A2 METAL COMPLEXES, METHODS, AND USES THEREOF ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2014-07-17 WO disclosed
WO-2014109814-A2 METAL COMPLEXES, METHODS, AND USES THEREOF ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2014-07-17 WO disclosed
CN-103476781-A Novel tetradentate platinum complexes UNIVERSAL DISPLAY CORP 2013-12-25 CN disclosed
CN-103183691-A 6-mesitylene-6H-6-boron hetero benzo[cd]pyrene derivative containing substituted or non-substituted carbazolyl, and preparation method and application thereof, and luminescent device comprising same KUNSHAN VISIONOX DISPLAY TECH 2013-07-03 CN disclosed
US-7314769-B2 Organometallic complex and light-emitting element containing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-01 US disclosed
US-6998492-B2 Organometallic complex and light-emitting element containing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-02-14 US disclosed
US-20050033054-A1 Organometallic complex and light-emitting element containing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2005-02-10 US disclosed
US-20040230061-A1 Organometallic complex and light-emitting element containing the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2004-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11910701-B2 Organic electroluminescent materials and devices ICOSLG, PDCD1LG2, NECTIN4 AHR 1612/4885AURKA 1837/4885KIF11 2462/4885
US-20050033054-A1 Organometallic complex and light-emitting element containing the same BCKDK, CCNK, CDK20 AHR 122/4885AURKA 346/4885KIF11 3005/4885
US-20260035398-A1 TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES LBR, SCO2, RAD54L AHR 298/4885AURKA 1969/4885KIF11 4839/4885
US-12043633-B2 Metal complexes, methods, and uses thereof SOD1, SOD3, XRCC6 AHR 3389/4885AURKA 3565/4885KIF11 1506/4885
US-12312366-B2 Tetradentate and octahedral metal complexes containing naphthyridinocarbazole and its analogues PAICS, DNTT, PNPO AHR 2686/4885AURKA 1043/4885KIF11 1936/4885
US-20240376140-A1 Metal Complexes, Methods, and Uses Thereof SOD1, SOD3, XRCC6 AHR 3389/4885AURKA 3565/4885KIF11 1506/4885
US-20230309376-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, PDCD1LG2, NECTIN4 AHR 1612/4885AURKA 1837/4885KIF11 2462/4885
US-12550604-B2 Organic electroluminescent materials and devices ROS1, DNMT3A, PRDM9 AHR 794/4885AURKA 4037/4885KIF11 3113/4885
US-20040230061-A1 Organometallic complex and light-emitting element containing the same NR0B1, BCKDK, NR4A1 AHR 186/4885AURKA 613/4885KIF11 3166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.