SCHEMBL21320126

SCHEMBL21320126

Cc1cccc2c1c1ccccc1n2-c1cccc(-c2ccc3c4ccccc4n(-c4ccccc4)c3c2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.47
KDM4E B2RXH2 2/20 0.47
ATM Q13315 1/20 0.47
AVPR1A P37288 1/20 0.36
RXFP1 Q9HBX9 2/20 0.36
KMT2A Q03164 4/20 0.35
IL1R1 P14778 1/20 0.35
ALDH1A1 P00352 4/20 0.35
ALKBH5 Q6P6C2 1/20 0.35
FTO Q9C0B1 1/20 0.35
MEN1 O00255 3/20 0.35
MAPT P10636 2/20 0.35
HTT P42858 1/20 0.35
GAA P10253 2/20 0.34
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
LMNA P02545 1/20 0.34
PLA2G10 O15496 1/20 0.34
TNKS2 Q9H2K2 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21319977 0.93 KDM4E (0.49) L3MBTL1KDM4EATMAVPR1ARXFP1
SCHEMBL19010475 0.92 AVPR1A (0.43) L3MBTL1KDM4EATMAVPR1ARXFP1
SCHEMBL23606166 0.90 KDM4E (0.46) L3MBTL1KDM4EATMRXFP1KMT2A
SCHEMBL19769492 0.89 L3MBTL1 (0.53) L3MBTL1KDM4EATMAVPR1ARXFP1
SCHEMBL18126073 0.89 L3MBTL1 (0.53) L3MBTL1KDM4EATMAVPR1ARXFP1
SCHEMBL19797668 0.88 L3MBTL1 (0.51) L3MBTL1KDM4EATMAVPR1ARXFP1
SCHEMBL19769536 0.88 L3MBTL1 (0.51) L3MBTL1KDM4EATMAVPR1ARXFP1
SCHEMBL19238811 0.87 L3MBTL1 (0.62) L3MBTL1KDM4EATMAVPR1AKMT2A
SCHEMBL20878493 0.87 L3MBTL1 (0.47) L3MBTL1KDM4EATMAVPR1ARXFP1
SCHEMBL19769514 0.86 L3MBTL1 (0.50) L3MBTL1KDM4EATMAVPR1ARXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3015465-B1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2019-09-04 EP disclosed