Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | RAC2 | P15153 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17714882 | 0.91 | KDM4E (0.33) | ATMKDM4EL3MBTL1NPC1POLB | |
| SCHEMBL16726774 | 0.90 | L3MBTL1 (0.45) | ATMKDM4EL3MBTL1NPC1POLB | |
| SCHEMBL22459480 | 0.88 | L3MBTL1 (0.45) | ATMKDM4EL3MBTL1HDAC4CHRNA7 | |
| SCHEMBL18708355 | 0.87 | NPC1 (0.37) | ATMKDM4EL3MBTL1NPC1POLB | |
| SCHEMBL4546808 | 0.86 | L3MBTL1 (0.50) | ATMKDM4EL3MBTL1NPC1POLB | |
| SCHEMBL17342659 | 0.85 | L3MBTL1 (0.49) | ATMKDM4EL3MBTL1HDAC4CHRNA7 | |
| SCHEMBL22068512 | 0.85 | KDM4E (0.40) | ATMKDM4EL3MBTL1NPC1POLB | |
| SCHEMBL17952785 | 0.85 | KDM4E (0.42) | ATMKDM4EL3MBTL1NPC1POLB | |
| SCHEMBL17952774 | 0.85 | KDM4E (0.42) | ATMKDM4EL3MBTL1NPC1POLB | |
| SCHEMBL23078816 | 0.84 | NPC1 (0.37) | ATMKDM4EL3MBTL1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3015465-B1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | LG CHEMICAL LTD (KR) | 2019-09-04 | — | — | EP | disclosed |