SCHEMBL21322009

SCHEMBL21322009

CCCCCc1ccc(-c2ccc(-c3ccc(OC)c(F)c3)c(F)c2)c(F)c1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.50
MGLL Q99685 4/20 0.47
CYP17A1 P05093 1/20 0.46
PPARG P37231 1/20 0.45
PPARA Q07869 1/20 0.45
RARA P10276 1/20 0.44
RARG P13631 1/20 0.44
ALOX5 P09917 1/20 0.43
GABRA1 P14867 1/20 0.43
GABRB2 P47870 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6060276 0.91 MGLL (0.46) RARBMGLLCYP17A1PPARGPPARA
SCHEMBL6059679 0.90 MGLL (0.47) RARBMGLLCYP17A1PPARGPPARA
SCHEMBL6059906 0.90 MGLL (0.47) RARBMGLLCYP17A1PPARGPPARA
SCHEMBL11222002 0.89 PPARG (0.54) PPARGPPARA
SCHEMBL6060553 0.87 MGLL (0.46) RARBMGLLCYP17A1ALOX5GABRA1
SCHEMBL3169159 0.87 RARB (0.42) RARBMGLLCYP17A1PPARGPPARA
SCHEMBL19309371 0.87 PPARG (0.56) PPARGPPARA
SCHEMBL12740134 0.87 RARB (0.48) RARBMGLLCYP17A1PPARGPPARA
SCHEMBL27316914 0.87 RARB (0.54) RARBRARARARG
SCHEMBL3152882 0.86 RARB (0.44) RARBMGLLCYP17A1PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3257839-B1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-09-04 EP disclosed