Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.56 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK3 | P49761 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21264511 | 1.00 | MET (0.56) | METNQO2CXCR1AVPR1BHRH3 | |
| SCHEMBL21264623 | 0.91 | MET (0.47) | METNQO2CTSAMAOBAKT1 | |
| SCHEMBL21322327 | 0.91 | MET (0.47) | METNQO2CTSAMAOBAKT1 | |
| SCHEMBL21322098 | 0.89 | MET (0.69) | METNQO2CXCR1AVPR1BHRH3 | |
| SCHEMBL21264611 | 0.89 | MET (0.69) | METNQO2CXCR1AVPR1BHRH3 | |
| SCHEMBL21322326 | 0.88 | MET (0.45) | METNQO2 | |
| SCHEMBL21264622 | 0.88 | MET (0.45) | METNQO2 | |
| SCHEMBL21264640 | 0.83 | MET (0.55) | METNQO2CXCR1HRH3ACHE | |
| SCHEMBL21322208 | 0.81 | MET (0.81) | METNQO2CXCR1AVPR1BCTSA | |
| SCHEMBL21264639 | 0.81 | MET (0.81) | METNQO2CXCR1AVPR1BCTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3533787-B1 | PYRIDONE COMPOUND AS C-MET INHIBITOR | FUJIAN COSUNTER PHARMACEUTICAL CO LTD (CN) | 2020-09-30 | — | — | EP | disclosed |
| EP-3533787-A1 | PYRIDONE COMPOUND AS C-MET INHIBITOR | Fujian Cosunter Pharmaceutical Co., Ltd. (CN) | 2019-09-04 | — | — | EP | disclosed |