Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | LDHA | P00338 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104850 | 0.94 | SLC6A4 (0.69) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| Ammonia Solution, Strong SCHEMBL8170665 | 0.91 | SLC6A4 (0.67) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| Iodide SCHEMBL28694313 | 0.89 | SLC6A4 (0.64) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| Bromide SCHEMBL28700903 | 0.89 | SLC6A4 (0.64) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| Hydrochloric Acid SCHEMBL28699626 | 0.89 | SLC6A4 (0.64) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL13719143 | 0.88 | SLC6A4 (0.62) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL19865658 | 0.88 | SLC6A4 (0.62) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL20781017 | 0.84 | SLC6A4 (0.58) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL13623704 | 0.83 | SLC6A4 (0.62) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA | |
| SCHEMBL6017470 | 0.83 | SLC6A4 (0.62) | SLC6A4CYP1A2CYP2D6CYP2C19LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190270726-A1 | PRODUCTS OF CHIRAL SYNTHESIS OF CIS-IMIDAZOLINE COMPOUNDS AND THEIR USE | UNITY BIOTECHNOLOGY, INC. | 2019-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190270726-A1 | PRODUCTS OF CHIRAL SYNTHESIS OF CIS-IMIDAZOLINE COMPOUNDS AND THEIR USE | MDM2, CDKN1A, TP53 | SLC6A4 4631/4885CYP1A2 927/4885CYP2D6 2680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.