Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8170665

COc1ccc(CC(C)C)cc1.N

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 0.67
CYP1A2 P05177 1/20 0.57
CYP2D6 P10635 1/20 0.57
CYP2C19 P33261 1/20 0.57
LDHA P00338 1/20 0.57
IDO1 P14902 2/20 0.52
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
AOC3 Q16853 1/20 0.49
AGXT P21549 1/20 0.48
LTA4H P09960 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL28700903 0.98 SLC6A4 (0.64) SLC6A4CYP1A2CYP2D6CYP2C19LDHA
Hydrochloric Acid SCHEMBL28699626 0.98 SLC6A4 (0.64) SLC6A4CYP1A2CYP2D6CYP2C19LDHA
Iodide SCHEMBL28694313 0.98 SLC6A4 (0.64) SLC6A4CYP1A2CYP2D6CYP2C19LDHA
SCHEMBL104850 0.98 SLC6A4 (0.69) SLC6A4CYP1A2CYP2D6CYP2C19LDHA
SCHEMBL21323940 0.91 SLC6A4 (0.62) SLC6A4CYP1A2CYP2D6CYP2C19LDHA
SCHEMBL19865658 0.91 SLC6A4 (0.62) SLC6A4CYP1A2CYP2D6CYP2C19LDHA
SCHEMBL13719143 0.91 SLC6A4 (0.62) SLC6A4CYP1A2CYP2D6CYP2C19LDHA
Acetic Acid SCHEMBL28687880 0.89 LDHA (0.66) SLC6A4LDHA
Sulfuric Acid SCHEMBL28679091 0.89 LDHA (0.56) SLC6A4CYP1A2CYP2D6CYP2C19LDHA
SCHEMBL2913839 0.86 SLC6A4 (0.56) SLC6A4CYP1A2CYP2D6CYP2C19LDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114057590-A Synthetic method of key intermediate of odaterol 安徽有吉医药科技有限公司 2022-02-18 CN claimed
CN-114057590-A Synthetic method of key intermediate of odaterol 安徽有吉医药科技有限公司 2022-02-18 CN disclosed
EP-0973730-A1 CALCILYTIC COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2000-01-26 EP disclosed
WO-1998045255-A1 CALCILYTIC COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 1998-10-15 WO disclosed