Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21331750 | 0.85 | EGFR (0.74) | EGFR | |
| SCHEMBL30167114 | 0.83 | EGFR (0.71) | EGFR | |
| SCHEMBL30167219 | 0.82 | EGFR (0.69) | EGFR | |
| SCHEMBL30167243 | 0.82 | EGFR (0.69) | EGFR | |
| SCHEMBL30167185 | 0.82 | EGFR (0.69) | EGFR | |
| SCHEMBL28514262 | 0.80 | EGFR (0.76) | EGFR | |
| SCHEMBL30167149 | 0.80 | EGFR (0.67) | EGFR | |
| SCHEMBL30167138 | 0.80 | EGFR (0.67) | EGFR | |
| SCHEMBL30167115 | 0.80 | EGFR (0.66) | EGFR | |
| SCHEMBL30167142 | 0.80 | EGFR (0.66) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110229172-B | Acyl-substituted oxazine quinazoline compound, preparation method and application thereof | 北京赛特明强医药科技有限公司 | 2020-12-25 | — | — | CN | disclosed |
| WO-2019170086-A1 | ACYL-SUBSTITUTED OXAZINO-QUINAZOLINE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | 北京赛特明强医药科技有限公司 | 2019-09-12 | — | — | WO | disclosed |
| WO-2019170086-A1 | ACYL-SUBSTITUTED OXAZINO-QUINAZOLINE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | 北京赛特明强医药科技有限公司 | 2019-09-12 | — | — | WO | disclosed |