Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CPS1 | P31327 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21342460 | 0.82 | KMT2A (0.44) | PRKCZKMT2AGAASMN1; SMN2MEN1 | |
| SCHEMBL13848578 | 0.82 | SMN1; SMN2 (0.42) | KMT2AGAASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL16695369 | 0.81 | PDE2A (0.51) | KMT2AGAASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL28616470 | 0.80 | KMT2A (0.47) | KMT2AGAASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL2430950 | 0.80 | MAPT (0.52) | KMT2AGAASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL6522396 | 0.79 | SMN1; SMN2 (0.56) | KMT2AGAASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL20718828 | 0.79 | MAPT (0.43) | KMT2AGAASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL29853528 | 0.79 | MAPT (0.43) | KMT2AGAASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL5040728 | 0.78 | PRKCZ (0.44) | PRKCZKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL5040727 | 0.78 | PRKCZ (0.44) | PRKCZKMT2AGAAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |
| WO-2019170904-A1 | PIPERIDINES OR PIPERIDONES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-09-12 | — | — | WO | disclosed |