Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | HTT | P42858 | 6/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21333750 | 0.89 | MAPT (0.39) | LMNAMAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL21350650 | 0.87 | MAPT (0.49) | LMNAMAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL8681706 | 0.81 | MAPT (0.38) | LMNAMAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL8680939 | 0.77 | MAPT (0.41) | LMNAMAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL8678924 | 0.77 | MAPT (0.38) | LMNAMAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL10595643 | 0.76 | MAPT (0.48) | LMNAMAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL8680051 | 0.76 | MAPT (0.49) | LMNAMAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL10418850 | 0.75 | MAPT (0.46) | LMNAMAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL8680344 | 0.75 | MAPT (0.44) | LMNAMAPTHTTSMN1; SMN2KMT2A | |
| SCHEMBL8681952 | 0.75 | MAPT (0.39) | LMNAMAPTSMN1; SMN2KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11618756-B2 | Compounds for coordinating with a metal, compositions containing such compounds, and methods of catalyzing reactions | PPG INDUSTRIES OHIO, INC. (US) | 2023-04-04 | — | — | US | disclosed |
| US-20210079009-A1 | Compounds for Coordinating with a Metal, Compositions Containing Such Compounds, and Methods of Catalyzing Reactions | PPG INDUSTRIES OHIO, INC. (US) | 2021-03-18 | — | — | US | disclosed |
| EP-3762143-A1 | COMPOUNDS FOR COORDINATING WITH A METAL, COMPOSITIONS CONTAINING SUCH COMPOUNDS, AND METHODS OF CATALYZING REACTIONS | PPG Industries Ohio Inc. (US) | 2021-01-13 | — | — | EP | disclosed |
| WO-2019173836-A1 | COMPOUNDS FOR COORDINATING WITH A METAL, COMPOSITIONS CONTAINING SUCH COMPOUNDS, AND METHODS OF CATALYZING REACTIONS | PPG INDUSTRIES OHIO, INC. (US) | 2019-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210079009-A1 | Compounds for Coordinating with a Metal, Compositions Containing Such Compounds, and Methods of Catalyzing Reactions | EPDR1, BRD2, EED | LMNA 1127/4885MAPT 4810/4885HTT 3676/4885 |
| US-11618756-B2 | Compounds for coordinating with a metal, compositions containing such compounds, and methods of catalyzing reactions | EPDR1, BRD2, EED | LMNA 1127/4885MAPT 4810/4885HTT 3676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.