Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | THRB | P10828 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8680238 | 0.85 | MAPT (0.55) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL29786745 | 0.84 | MAPT (0.56) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL1629606 | 0.84 | MAPT (0.56) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL10418903 | 0.83 | MAPT (0.43) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL8680344 | 0.82 | MAPT (0.44) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL8682721 | 0.81 | MAPT (0.56) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL25973516 | 0.81 | MEN1 (0.47) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL8680103 | 0.78 | MEN1 (0.46) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL8684941 | 0.77 | MAPT (0.41) | MAPTKDM4ELMNAGAAALDH1A1 | |
| SCHEMBL21333765 | 0.76 | LMNA (0.38) | MAPTKDM4ELMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4880667-A | SUNGLASSES, SPIROINDOLINE PHOTOCHROMIC COMPOUND | PPG INDUSTRIES, INC. (US) | 1989-11-14 | — | — | US | disclosed |