Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.37 |
| ▸ | PIP4K2A | P48426 | 2/20 | 0.36 |
| ▸ | XIAP | P98170 | 2/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21350307 | 0.88 | ELANE (0.42) | SLC22A12KDM4CPIP4K2AXIAPMAPK8 | |
| SCHEMBL21331842 | 0.88 | SLC22A12 (0.39) | SLC22A12KDM4CPIP4K2AFTOKDM6B | |
| SCHEMBL21331826 | 0.86 | CYP2C9 (0.50) | SLC22A12KDM4CPIP4K2ACYP2C9 | |
| SCHEMBL21350907 | 0.85 | SLC22A12 (0.57) | SLC22A12 | |
| SCHEMBL21331851 | 0.85 | SLC22A12 (0.44) | SLC22A12KDM4CPIP4K2AXIAPCYP2C9 | |
| SCHEMBL28408726 | 0.80 | SLC22A12 (0.46) | SLC22A12KDM4CFTOMAPK8MAPK9 | |
| SCHEMBL21350532 | 0.78 | ELANE (0.41) | SLC22A12MAPK8MAPK9MAPK10NAMPT | |
| SCHEMBL21350523 | 0.77 | SLC22A12 (0.48) | SLC22A12MAPK10CYP2C9 | |
| SCHEMBL21331858 | 0.77 | KMT2A (0.40) | SLC22A12CYP2C9NOTUM | |
| SCHEMBL21350518 | 0.77 | CYP2C9 (0.45) | CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440397-B | 3- (naphthalene-1-methyl substituted) pyridine derivative and synthesis method and application thereof | 南方医科大学 | 2020-06-05 | — | — | CN | disclosed |
| WO-2019169890-A1 | 3-(NAPHTHALENE-1-METHYL SUBSTITUTED)PYRIDINE DERIVATIVE, SYNTHETIC METHOD THEREFOR AND USE THEREOF | 南方医科大学 | 2019-09-12 | — | — | WO | disclosed |