Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21350532 | 0.90 | ELANE (0.41) | ELANESLC22A12TSHRTP53MAPK8 | |
| SCHEMBL21350518 | 0.89 | CYP2C9 (0.45) | ELANETSHRTP53LMNASMN1; SMN2 | |
| SCHEMBL21333904 | 0.88 | SLC22A12 (0.39) | SLC22A12MAPK8MAPK9MAPK10KDM4C | |
| SCHEMBL21350629 | 0.87 | PDCD1 (0.42) | ELANESLC22A12MAPK8MAPK9MAPK10 | |
| SCHEMBL21350517 | 0.87 | SLC22A12 (0.52) | ELANESLC22A12 | |
| SCHEMBL21350630 | 0.80 | LATS1 (0.45) | SLC22A12TP53MAPK8MAPK9MAPK10 | |
| SCHEMBL21350531 | 0.80 | KDM4E (0.38) | SLC22A12TSHRLMNASMN1; SMN2 | |
| SCHEMBL21350522 | 0.79 | SLC22A12 (0.44) | SLC22A12TSHRLMNASMN1; SMN2 | |
| SCHEMBL21331826 | 0.77 | CYP2C9 (0.50) | SLC22A12TSHRLMNASMN1; SMN2KDM4C | |
| SCHEMBL21331842 | 0.76 | SLC22A12 (0.39) | SLC22A12MAPK8MAPK9MAPK10DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019169890-A1 | 3-(NAPHTHALENE-1-METHYL SUBSTITUTED)PYRIDINE DERIVATIVE, SYNTHETIC METHOD THEREFOR AND USE THEREOF | 南方医科大学 | 2019-09-12 | — | — | WO | disclosed |