SCHEMBL21335108

SCHEMBL21335108

CC(C)C[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCN)NC(=O)[C@@H](NC(=O)[C@H](CCN)NC(=O)[C@@H](NC(=O)CC(C)O)C(C)O)CCNC(=O)C(C(C)O)NC(=O)[C@H](CCN)NC(=O)[C@H](CCN)NC1=O

nearest known ligand 0.82

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 3/20 0.82
▸ RCOR1 Q9UKL0 2/20 0.82
▸ TERF2 Q15554 1/20 0.42
▸ SSTR5 P35346 7/20 0.41
▸ SSTR4 P31391 6/20 0.41
▸ SSTR2 P30874 5/20 0.41
▸ TERF2IP Q9NYB0 2/20 0.39
▸ TEAD4 Q15561 1/20 0.39
▸ TEAD3 Q99594 1/20 0.39
▸ LDHB P07195 1/20 0.39
▸ KEAP1 Q14145 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16426294 1.00 KDM1A (0.82) KDM1ARCOR1TERF2SSTR5SSTR4
SCHEMBL21335145 0.95 KDM1A (0.88) KDM1ARCOR1TERF2SSTR5SSTR4
SCHEMBL16426328 0.95 KDM1A (0.84) KDM1ARCOR1TERF2SSTR5SSTR4
SCHEMBL16426297 0.95 KDM1A (0.88) KDM1ARCOR1TERF2SSTR5SSTR4
SCHEMBL25455822 0.95 KDM1A (0.77) KDM1ARCOR1TERF2SSTR5SSTR4
SCHEMBL20366251 0.95 KDM1A (0.77) KDM1ARCOR1TERF2SSTR5SSTR4
SCHEMBL25455642 0.95 KDM1A (0.77) KDM1ARCOR1TERF2SSTR5SSTR4
SCHEMBL25466596 0.95 KDM1A (0.77) KDM1ARCOR1TERF2SSTR5SSTR4
SCHEMBL21335298 0.94 KDM1A (0.83) KDM1ARCOR1TERF2SSTR5SSTR4
SCHEMBL21335212 0.94 KDM1A (0.89) KDM1ARCOR1TERF2SSTR5SSTR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200188476-A1 ANTI-MICROBIAL AGENT-POLYMER CONJUGATES AND METHODS OF USE THEREOF UNIV CALIFORNIA (US) 2020-06-18 — — US disclosed
US-10407467-B2 Polymyxin derivatives and their use in combination therapy together with different antibiotics NEW PHARMA LICENCE HOLDINGS LIMITED (MT) 2019-09-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200188476-A1 ANTI-MICROBIAL AGENT-POLYMER CONJUGATES AND METHODS OF USE THEREOF DDOST, MGAM, MSN KDM1A 3829/4885RCOR1 4860/4885TERF2 4009/4885
US-10407467-B2 Polymyxin derivatives and their use in combination therapy together with different antibiotics MRPS18A, MRPL21, RRP1B KDM1A 3699/4885RCOR1 1566/4885TERF2 2676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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