Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 11/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.34 |
| ▸ | PPARA | Q07869 | 7/20 | 0.34 |
| ▸ | PTGES | O14684 | 6/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2135135 | 0.95 | HSD17B10 (0.40) | HSD17B10CA2MAPK1PPARGALOX5 | |
| SCHEMBL2137087 | 0.94 | HSD17B10 (0.39) | HSD17B10CA2MAPK1PPARGALOX5 | |
| SCHEMBL2135946 | 0.92 | HSD17B10 (0.42) | HSD17B10CA2MAPK1PPARGALOX5 | |
| SCHEMBL2135520 | 0.92 | CHRM1 (0.33) | HSD17B10CA2MAPK1PPARAMAPT | |
| SCHEMBL2135821 | 0.91 | HSD17B10 (0.39) | HSD17B10CA2MAPK1PPARGALOX5 | |
| SCHEMBL2133224 | 0.90 | HSD17B10 (0.39) | HSD17B10CA2MAPK1PPARGALOX5 | |
| SCHEMBL2133227 | 0.88 | HSD17B10 (0.33) | HSD17B10MAPTEPHX1CES1 | |
| SCHEMBL2134330 | 0.88 | HSD17B10 (0.43) | HSD17B10CA2MAPK1PPARGALOX5 | |
| SCHEMBL2135006 | 0.87 | HSD17B10 (0.39) | HSD17B10CA2MAPK1PPARGALOX5 | |
| SCHEMBL2134788 | 0.87 | EPHX1 (0.34) | HSD17B10MAPTEPHX1CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101294-A1 | PROCESS FOR PRODUCING (FLUOROALKYLTHIO) ACETIC ACID ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101294-A1 | PROCESS FOR PRODUCING (FLUOROALKYLTHIO) ACETIC ACID ESTER | GRHPR, AKR7A2, FAR1 | HSD17B10 232/4885CA2 737/4885MAPK1 1590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.