SCHEMBL213360

SCHEMBL213360

CC(=O)O/N=C/c1cnccn1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CTH P32929 1/20 0.43
ADORA3 P0DMS8 1/20 0.38
TSHR P16473 1/20 0.38
MC4R P32245 1/20 0.38
ADRA1A P35348 1/20 0.38
MC3R P41968 1/20 0.38
RAB9A P51151 1/20 0.36
KMT2A Q03164 1/20 0.36
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
FAAH O00519 11/20 0.35
NAPRT Q6XQN6 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
GAA P10253 2/20 0.35
MAPT P10636 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL213361 1.00 CTH (0.43) CTHADORA3TSHRMC4RADRA1A
SCHEMBL214327 0.77 CTH (0.45) CTHRAB9AKMT2AKDM4EGAA
SCHEMBL214326 0.77 CTH (0.45) CTHRAB9AKMT2AKDM4EGAA
SCHEMBL213987 0.77 KDM4E (0.50) RAB9AKMT2AKDM4EALDH1A1CYP1A2
SCHEMBL213988 0.77 KDM4E (0.50) RAB9AKMT2AKDM4EALDH1A1CYP1A2
SCHEMBL212422 0.74 CTH (0.43) CTHRAB9AKMT2A
SCHEMBL212423 0.74 CTH (0.43) CTHRAB9AKMT2A
SCHEMBL213439 0.72 CTH (0.42) CTHRAB9AKMT2A
SCHEMBL17716524 0.70
SCHEMBL3852880 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120077941-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2012-03-29 US claimed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US claimed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US claimed
US-8541509-B2 Polymers functionalized with protected oxime compounds BRIDGESTONE CORPORATION (JP) 2013-09-24 US disclosed
US-20120077941-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2012-03-29 US disclosed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US disclosed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US disclosed