Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16783734 | 0.90 | KDM4E (0.41) | ALDH1A1L3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL16806402 | 0.89 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL16783779 | 0.88 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL16783515 | 0.88 | NPC1 (0.44) | ALDH1A1LMNAKDM5BCYP1A2MEN1 | |
| SCHEMBL16783746 | 0.82 | NPSR1 (0.41) | ALDH1A1CYP1A2MEN1KMT2ALIPE | |
| SCHEMBL16783503 | 0.78 | KDM4E (0.38) | ALDH1A1MEN1KMT2ACYP2C9CYP2C19 | |
| Bromide SCHEMBL16783693 | 0.78 | ALDH1A1 (0.40) | ALDH1A1ADRA1DADRA1AADRA1BL3MBTL1 | |
| SCHEMBL16806441 | 0.78 | KDM5B (0.43) | ALDH1A1LMNAKDM5BCYP1A2MEN1 | |
| SCHEMBL16806412 | 0.78 | KDM5B (0.43) | ALDH1A1LMNAKDM5BCYP1A2MEN1 | |
| Hydrochloric Acid SCHEMBL16783737 | 0.77 | KDM5B (0.43) | ALDH1A1LMNAKDM5BCYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083617-B1 | ISOCHROMENE DERIVATIVES AS PHOSPHOINOSITIDE 3-KINASES INHIBITORS | CHIESI FARM SPA (IT) | 2019-09-11 | — | — | EP | disclosed |