Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 3/20 | 0.68 |
| ▸ | JAK3 | P52333 | 1/20 | 0.68 |
| ▸ | EGFR | P00533 | 16/20 | 0.68 |
| ▸ | ITK | Q08881 | 5/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976710 | 0.92 | BTK (0.69) | BTKJAK3EGFRITK | |
| SCHEMBL12519542 | 0.91 | EGFR (0.79) | BTKJAK3EGFRITK | |
| SCHEMBL12519536 | 0.89 | EGFR (0.82) | BTKJAK3EGFRITK | |
| SCHEMBL21338051 | 0.88 | ITK (0.68) | BTKJAK3EGFRITK | |
| SCHEMBL16370821 | 0.87 | EGFR (0.65) | BTKJAK3EGFRITK | |
| SCHEMBL30672892 | 0.87 | EGFR (0.65) | BTKJAK3EGFRITK | |
| SCHEMBL16370711 | 0.87 | EGFR (0.62) | BTKJAK3EGFRITK | |
| SCHEMBL30672900 | 0.87 | EGFR (0.62) | BTKJAK3EGFRITK | |
| SCHEMBL16706331 | 0.86 | BTK (0.62) | BTKJAK3EGFRITK | |
| SCHEMBL21338057 | 0.85 | EGFR (0.72) | BTKJAK3EGFRITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019496-B1 | PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS | ACEA THERAPEUTICS INC (US) | 2019-09-11 | — | — | EP | disclosed |