Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 8/20 | 0.68 |
| ▸ | BTK | Q06187 | 2/20 | 0.67 |
| ▸ | JAK3 | P52333 | 1/20 | 0.67 |
| ▸ | EGFR | P00533 | 14/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16371083 | 0.89 | EGFR (0.61) | ITKBTKJAK3EGFR | |
| SCHEMBL16371085 | 0.89 | EGFR (0.61) | ITKBTKJAK3EGFR | |
| SCHEMBL19976710 | 0.89 | BTK (0.69) | ITKBTKJAK3EGFR | |
| SCHEMBL21338050 | 0.88 | BTK (0.68) | ITKBTKJAK3EGFR | |
| SCHEMBL12519542 | 0.88 | EGFR (0.79) | ITKBTKJAK3EGFR | |
| SCHEMBL16698313 | 0.87 | EGFR (0.57) | ITKBTKJAK3EGFR | |
| SCHEMBL16698117 | 0.87 | ITK (0.56) | ITKBTKJAK3EGFR | |
| SCHEMBL16391060 | 0.87 | EGFR (0.57) | ITKBTKJAK3EGFR | |
| SCHEMBL16698119 | 0.87 | ITK (0.56) | ITKBTKJAK3EGFR | |
| SCHEMBL16391061 | 0.87 | EGFR (0.57) | ITKBTKJAK3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019496-B1 | PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS | ACEA THERAPEUTICS INC (US) | 2019-09-11 | — | — | EP | disclosed |