Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 6/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844689 | 0.88 | MAPT (0.37) | RXFP1ALDH1A1MAPTPOLBHSD17B10 | |
| SCHEMBL13066604 | 0.85 | ALDH1A1 (0.38) | ALDH1A1MAPTPOLBHSD17B10L3MBTL1 | |
| SCHEMBL843885 | 0.84 | POLB (0.38) | ALDH1A1MAPTPOLBHSD17B10L3MBTL1 | |
| SCHEMBL16743445 | 0.80 | MAPT (0.37) | RXFP1ALDH1A1MAPTPOLBL3MBTL1 | |
| SCHEMBL13082349 | 0.78 | ALDH1A1 (0.36) | RXFP1ALDH1A1MAPTPOLBHSD17B10 | |
| SCHEMBL844535 | 0.77 | ALDH1A1 (0.39) | RXFP1ALDH1A1MAPTPOLBHSD17B10 | |
| SCHEMBL844555 | 0.77 | NPSR1 (0.39) | ALDH1A1MAPTPOLBHSD17B10L3MBTL1 | |
| SCHEMBL16998613 | 0.76 | MEN1 (0.35) | ALDH1A1POLBHSD17B10L3MBTL1HPGD | |
| SCHEMBL844534 | 0.74 | MEN1 (0.36) | ALDH1A1MAPTPOLBHSD17B10L3MBTL1 | |
| SCHEMBL13066862 | 0.74 | ALDH1A1 (0.36) | RXFP1ALDH1A1MAPTPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432776-B1 | METHYL SULFANYL PYRIMIDINES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS | UNIV LAVAL (CA) | 2019-09-11 | — | — | EP | disclosed |