Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320553 | 0.84 | TDP1 (0.41) | TDP1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL10490625 | 0.82 | TDP1 (0.57) | TDP1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL8459678 | 0.81 | TRPA1 (0.41) | TDP1LMNAMEN1KMT2AMAPT | |
| SCHEMBL27717239 | 0.80 | TDP1 (0.55) | TDP1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL7161146 | 0.80 | TDP1 (0.55) | TDP1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL28033674 | 0.80 | TDP1 (0.55) | TDP1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL23667707 | 0.79 | TDP1 (0.50) | TDP1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL21491245 | 0.79 | TDP1 (0.50) | TDP1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL21491365 | 0.79 | TDP1 (0.50) | TDP1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL5085882 | 0.79 | TRPA1 (0.40) | TDP1LMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432776-B1 | METHYL SULFANYL PYRIMIDINES USEFUL AS ANTIINFLAMMATORIES, ANALGESICS, AND ANTIEPILEPTICS | UNIV LAVAL (CA) | 2019-09-11 | — | — | EP | disclosed |