Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.39 |
| ▸ | DPP4 | P27487 | 6/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.39 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21339222 | 1.00 | DPP8 (0.39) | DPP8DPP4DPP7DPP9GRM1 | |
| SCHEMBL21339233 | 1.00 | DPP8 (0.39) | DPP8DPP4DPP7DPP9GRM1 | |
| SCHEMBL21339218 | 1.00 | DPP8 (0.39) | DPP8DPP4DPP7DPP9GRM1 | |
| SCHEMBL21339248 | 0.89 | GRM1 (0.34) | DPP8DPP4DPP7DPP9GRM1 | |
| SCHEMBL21339006 | 0.89 | GRM1 (0.34) | DPP8DPP4DPP7DPP9GRM1 | |
| SCHEMBL21339256 | 0.89 | GRM1 (0.34) | DPP8DPP4DPP7DPP9GRM1 | |
| SCHEMBL21339239 | 0.89 | GRM1 (0.34) | DPP8DPP4DPP7DPP9GRM1 | |
| SCHEMBL21339029 | 0.89 | GRM1 (0.34) | DPP8DPP4DPP7DPP9GRM1 | |
| SCHEMBL21339217 | 0.89 | GRM1 (0.34) | DPP8DPP4DPP7DPP9GRM1 | |
| SCHEMBL21339258 | 0.89 | GRM1 (0.34) | DPP8DPP4DPP7DPP9GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230049481-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2023-02-16 | — | — | US | disclosed |
| US-11155520-B2 | Picolinamides as fungicides | DOW AGROSCIENCES LLC | 2021-10-26 | — | — | US | disclosed |
| US-20200399222-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2020-12-24 | — | — | US | disclosed |
| US-20190276404-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2019-09-12 | — | — | US | disclosed |
| WO-2019173665-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2019-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399222-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | DPP8 202/4885DPP4 557/4885DPP7 146/4885 |
| US-20190276404-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | DPP8 202/4885DPP4 557/4885DPP7 146/4885 |
| US-20230049481-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | DPP8 202/4885DPP4 557/4885DPP7 146/4885 |
| US-11155520-B2 | Picolinamides as fungicides | CYP1A2, CYP4F12, FKBP2 | DPP8 202/4885DPP4 557/4885DPP7 146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.