⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17253332 | 0.81 | HCAR2 (0.37) | — | |
| SCHEMBL12812138 | 0.78 | — | — | |
| SCHEMBL256105 | 0.76 | — | — | |
| SCHEMBL18779703 | 0.74 | — | — | |
| SCHEMBL13594181 | 0.74 | — | — | |
| SCHEMBL13075767 | 0.74 | — | — | |
| SCHEMBL7720569 | 0.73 | — | — | |
| SCHEMBL5020589 | 0.73 | — | — | |
| SCHEMBL4572535 | 0.73 | — | — | |
| SCHEMBL19453051 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10646469-B2 | Substituted indole derivatives as dengue viral replication inhibitors | Janssen Pharmaceuticals, Inc. (US) | 2020-05-12 | — | — | US | disclosed |
| US-20190274999-A1 | Substituted Indole Derivatives As Dengue Viral Replication Inhibitors | Janssen Pharmaceuticals, Inc. (US) | 2019-09-12 | — | — | US | disclosed |