SCHEMBL21339965

SCHEMBL21339965

COC(=O)c1ccc(/C(=N/N)NN)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.61
CA1 P00915 4/20 0.52
CA2 P00918 4/20 0.52
CA12 O43570 3/20 0.52
CA9 Q16790 3/20 0.52
CA14 Q9ULX7 3/20 0.52
TDP1 Q9NUW8 1/20 0.52
CA7 P43166 1/20 0.52
LOXL2 Q9Y4K0 1/20 0.50
STS P08842 1/20 0.50
TSHR P16473 1/20 0.48
RAB9A P51151 2/20 0.47
CASP3 P42574 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.45
MEN1 O00255 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28704033 0.79 CA1 (0.76) MAPTCA1CA2CA12CA9
SCHEMBL23118889 0.79 TSHR (0.50) CA1CA2CA12CA9CA14
SCHEMBL23600 0.77 CA1 (0.80) MAPTCA1CA2CA12CA9
SCHEMBL28993944 0.77 CA1 (0.80) MAPTCA1CA2CA12CA9
SCHEMBL1302573 0.76 MAPT (1.00) MAPTCA1CA2CA12CA9
Urea SCHEMBL20838278 0.75 CA1 (0.70) MAPTCA1CA2CA12CA9
SCHEMBL18758174 0.75 CA1 (0.51) MAPTCA1CA2RAB9ACASP3
Water SCHEMBL22720573 0.75 CA1 (0.76) MAPTCA1CA2CA12CA9
SCHEMBL28531063 0.75 CA1 (0.76) MAPTCA1CA2CA12CA9
Methyl Alcohol SCHEMBL28561085 0.75 CA1 (0.76) MAPTCA1CA2CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019171234-A9 HETEROCYCLIC COMPOUNDS AS FUNGICIDES PI INDUSTRIES LTD. (IN) 2020-01-09 WO disclosed
WO-2019171234-A1 HETEROCYCLIC COMPOUNDS AS FUNGICIDES PI INDUSTRIES LTD. (IN) 2019-09-12 WO disclosed