SCHEMBL21339985

SCHEMBL21339985

Clc1cccc2c1oc1c2ccc2c3ccccc3oc21

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AHR P35869 7/20 0.53
TTR P02766 4/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
ALOX5 P09917 3/20 0.42
MAOA P21397 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP2A6 P11509 1/20 0.39
PIM1 P11309 1/20 0.39
CSNK2A2 P19784 1/20 0.39
CSNK2B P67870 1/20 0.39
PIM3 Q86V86 1/20 0.39
PIM2 Q9P1W9 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21975632 0.96 AHR (0.53) AHRTTRSMN1; SMN2ALOX5MAOA
SCHEMBL2283190 0.94 AHR (0.58) AHRTTRSMN1; SMN2ALOX5MAOA
SCHEMBL24071857 0.90 AHR (0.53) AHRTTRSMN1; SMN2MAOACYP1A2
SCHEMBL22129979 0.89 ALOX5 (0.55) AHRTTRSMN1; SMN2ALOX5PIM1
SCHEMBL18339171 0.87 AHR (0.56) AHRTTRSMN1; SMN2ALOX5MAOA
SCHEMBL24090333 0.87 AHR (0.54) AHRTTRSMN1; SMN2ALOX5MAOA
SCHEMBL22698058 0.86 AHR (0.55) AHRSMN1; SMN2ALOX5MAOACYP1A2
SCHEMBL21975357 0.85 AHR (0.57) AHRTTRSMN1; SMN2ALOX5MAOA
SCHEMBL21204279 0.85 AHR (0.65) AHRTTRSMN1; SMN2ALOX5MAOA
SCHEMBL22129987 0.84 AHR (0.54) AHRTTRSMN1; SMN2ALOX5KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-16 US disclosed
US-11746122-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-05 US disclosed
US-11746122-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-09-05 US disclosed
US-20220135606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-05-05 US disclosed
US-11279722-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-03-22 US disclosed
US-20210380534-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2021-12-09 US disclosed
US-11165028-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-11-02 US disclosed
US-11142538-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-10-12 US disclosed
US-20200199163-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-25 US disclosed
US-20200048290-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-02-13 US disclosed
EP-3539959-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2019-09-18 EP disclosed
US-20190280219-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210380534-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OCIAD2, OSTC AHR 2169/4885TTR 1689/4885SMN1; SMN2 4263/4885
US-20190280219-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ESRRG, ESR2, GLRA2 AHR 548/4885TTR 3615/4885SMN1; SMN2 3066/4885
US-20220135606-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES GLRA3, GLRA2, LIFR AHR 2934/4885TTR 3682/4885SMN1; SMN2 3281/4885
US-11279722-B2 Organic electroluminescent materials and devices GLRA3, GLRA2, LIFR AHR 2930/4885TTR 3717/4885SMN1; SMN2 3318/4885
US-20200048290-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ESRRG, ESR2, GLRA2 AHR 548/4885TTR 3615/4885SMN1; SMN2 3066/4885
US-11746122-B2 Organic electroluminescent materials and devices GLRA3, GLRA2, LIFR AHR 2934/4885TTR 3682/4885SMN1; SMN2 3281/4885
US-11142538-B2 Organic electroluminescent materials and devices ESRRG, ESR2, GLRA2 AHR 548/4885TTR 3615/4885SMN1; SMN2 3066/4885
US-20230365607-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OR10J3 AHR 1670/4885TTR 2141/4885SMN1; SMN2 1311/4885
US-11165028-B2 Organic electroluminescent materials and devices ESRRG, ESR2, GLRA2 AHR 548/4885TTR 3615/4885SMN1; SMN2 3066/4885
US-20200199163-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES GLRA3, GLRA2, LIFR AHR 2930/4885TTR 3717/4885SMN1; SMN2 3318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.