Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12257175 | 0.69 | TDP1 (0.39) | KDM4EALDH1A1RAB9ACACNA1BAPBA1 | |
| SCHEMBL1251696 | 0.66 | IDO1 (0.39) | KDM4EALDH1A1RAB9ACACNA1BAPBA1 | |
| SCHEMBL2282509 | 0.63 | IDO1 (0.34) | KDM4EALDH1A1RAB9ACACNA1BAPBA1 | |
| SCHEMBL2284408 | 0.62 | LMNA (0.46) | KDM4EALDH1A1 | |
| SCHEMBL9738439 | 0.61 | JAK3 (0.31) | — | |
| SCHEMBL25637787 | 0.61 | KDM4E (0.32) | KDM4EALDH1A1 | |
| SCHEMBL12257178 | 0.61 | TDP1 (0.39) | KDM4EALDH1A1KMT2A | |
| SCHEMBL12347478 | 0.60 | — | — | |
| SCHEMBL11630670 | 0.60 | LMNA (0.41) | KDM4EALDH1A1RAB9ACACNA1BAPBA1 | |
| SCHEMBL12257176 | 0.58 | TDP1 (0.41) | KDM4EALDH1A1RAB9ACACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019173653-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. (US) | 2019-09-12 | — | — | WO | disclosed |