SCHEMBL21340876

SCHEMBL21340876

CCCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCO)cc1C(C)(C)C

nearest known ligand 0.89

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RARG P13631 20/20 0.89
RARB P10826 19/20 0.89
RARA P10276 18/20 0.89

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL382316 0.96 RARG (0.89) RARGRARBRARA
SCHEMBL381691 0.94 RARG (1.00) RARGRARBRARA
SCHEMBL381853 0.93 RARG (0.85) RARGRARBRARA
SCHEMBL382382 0.92 RARG (1.00) RARGRARBRARA
SCHEMBL381776 0.91 RARG (1.00) RARGRARBRARA
SCHEMBL381976 0.86 RARG (0.84) RARGRARBRARA
SCHEMBL382248 0.86 RARG (0.80) RARGRARBRARA
SCHEMBL382966 0.85 RARG (0.70) RARGRARBRARA
SCHEMBL382031 0.85 RARG (0.82) RARGRARBRARA
SCHEMBL381682 0.84 RARG (0.81) RARGRARBRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10980778-B2 Methods for treating multiple osteochondroma (MO) Clementia Pharmaceuticals Inc. (CA) 2021-04-20 US disclosed
US-20190275005-A1 METHODS FOR TREATING MULTIPLE OSTEOCHONDROMA (MO) Clementia Pharmaceuticals Inc. (CA) 2019-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10980778-B2 Methods for treating multiple osteochondroma (MO) UTRN, VHL, SOST RARG 1720/4885RARB 1620/4885RARA 1990/4885
US-20190275005-A1 METHODS FOR TREATING MULTIPLE OSTEOCHONDROMA (MO) UTRN, VHL, SOST RARG 1720/4885RARB 1620/4885RARA 1990/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.