SCHEMBL21342276

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25514525	0.86	CDK5 (0.38)	CDK5CDK5R1JAK3GSK3BALDH1A1
	SCHEMBL22817667	0.86	CDK5 (0.39)	CDK5CDK5R1JAK3GSK3BALDH1A1
	SCHEMBL19964717	0.85	EZH2 (0.39)	CDK5CDK5R1ALDH1A1KDM4EHPGD
	SCHEMBL21342364	0.85	EZH2 (0.45)	ALDH1A1KDM4EHPGDGAAGLA
	SCHEMBL21342274	0.83	EZH2 (0.39)	CDK5CDK5R1JAK3GSK3BEZH2
	SCHEMBL19964530	0.80	ALDH1A1 (0.46)	ALDH1A1KDM4EHPGDGAAGLA
	SCHEMBL21113045	0.79	ALDH1A1 (0.40)	ALDH1A1KDM4EHPGDGAAGLA
	SCHEMBL21156134	0.78	KDM4E (0.47)	JAK3ALDH1A1KDM4EHPGDGAA
	SCHEMBL19964421	0.77	SMARCA2 (0.51)	ALDH1A1KDM4EHPGDGAAMAPT
	SCHEMBL21342091	0.77	EZH2 (0.45)	ALDH1A1KDM4EHPGDGAAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.