Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22802156 | 0.74 | EZH2 (0.37) | RORC | |
| SCHEMBL22872284 | 0.74 | EZH2 (0.34) | RORC | |
| SCHEMBL21113275 | 0.68 | LRRK2 (0.33) | RORC | |
| SCHEMBL21113320 | 0.66 | EZH2 (0.38) | — | |
| SCHEMBL21113520 | 0.63 | EZH2 (0.49) | — | |
| SCHEMBL22872249 | 0.62 | EZH2 (0.39) | — | |
| SCHEMBL20038407 | 0.60 | — | — | |
| SCHEMBL21156605 | 0.59 | EED (0.52) | — | |
| SCHEMBL21113188 | 0.58 | EZH2 (0.35) | — | |
| SCHEMBL21113154 | 0.58 | EZH2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019170063-A1 | INDOLIZINE COMPOUNDS, PREPARATION METHOD AND USE THEREOF | 上海海和药物研究开发有限公司 | 2019-09-12 | — | — | WO | disclosed |