Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19416301 | 0.89 | NAMPT (0.41) | HPGDHTTSMN1; SMN2L3MBTL1NAMPT | |
| SCHEMBL14117838 | 0.86 | SMN1; SMN2 (0.40) | HPGDHTTSMN1; SMN2L3MBTL1NAMPT | |
| SCHEMBL12355355 | 0.85 | SMN1; SMN2 (0.39) | HPGDHTTSMN1; SMN2L3MBTL1NAMPT | |
| SCHEMBL21767041 | 0.85 | L3MBTL1 (0.37) | HPGDHTTSMN1; SMN2L3MBTL1NAMPT | |
| SCHEMBL11990467 | 0.85 | L3MBTL1 (0.50) | HPGDHTTSMN1; SMN2L3MBTL1CASP2 | |
| SCHEMBL20934157 | 0.85 | SMN1; SMN2 (0.39) | HPGDHTTSMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL18972339 | 0.84 | L3MBTL1 (0.52) | HPGDHTTSMN1; SMN2L3MBTL1CASP2 | |
| SCHEMBL10140378 | 0.84 | L3MBTL1 (0.52) | HPGDHTTSMN1; SMN2L3MBTL1CASP2 | |
| SCHEMBL19543157 | 0.84 | L3MBTL1 (0.45) | HPGDHTTSMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL20364047 | 0.83 | NAMPT (0.38) | HPGDHTTSMN1; SMN2L3MBTL1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019173639-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. (US) | 2019-09-12 | — | — | WO | disclosed |